SEMAGLUTIDE
- A GLP-1 receptor agonist (single pathway)
- Developed by Novo Nordisk
- Works by:
- reducing appetite
- slowing gastric emptying
- improving insulin response
Cycle length
- Same principle again:
- Semaglutide is NOT meant to be cycled
How it’s actually used:
- Designed for continuous, long-term use
- Clinical trials:
- Typically 68 weeks+
- Effects build gradually over months
Semaglutide 10 (10 mg/3ml/300units) 30 units = 1mg
- Weeks 1–4: 7 units weekly
- Weeks 5–8: 15 units weekly
Semaglutide 20 (20mg/3ml/300units) 15 units =1mg
- Weeks 9–12: 30 units weekly (This does is not for first time use)
- Weeks 13–16: 45 units weekly
- Weeks 17 Onwards: 60-75 units weekly (Repeat cycle until research is complete)
CAGRILINTIDE
- is an amylin analogue developed by Novo Nordisk.
- Mimics the hormone amylin (co-secreted with insulin)
- Works differently from GLP-1 drugs:
- increases satiety (you feel full faster)
- slows gastric emptying
- reduces food intake
- It’s often studied in combination with semaglutide (called “CagriSema”), which targets multiple appetite pathways.
Cycle length (research / real-world use)
- Same key principle as the others:
- Cagrilintide is NOT a cycle-based compound
In studies:
- Used as continuous therapy
- Trials typically run:
- 20–68 weeks+
- Effects build gradually over time
Cagrilintide 10 (10 mg/3ml/300units) 30 units = 1mg
- Weeks 1–4: 30 units weekly
- Weeks 5–8: 45 units weekly (Repeat cycle until research is complete)
Tissue Repair & Longevity
- GHK-Cu (short for glycyl-L-histidyl-L-lysine copper) is a naturally occurring copper-binding peptide found in human plasma, saliva, and urine. It’s very different from the weight-loss drugs you’ve been asking about.
What GHK-Cu is
- A tripeptide + copper ion
- Known for roles in:
- skin regeneration
- wound healing
- collagen production
- Widely used in cosmetics and dermatology research
What it’s studied for
- Research suggests GHK-Cu may:
- Stimulate collagen and elastin
- Improve skin elasticity and wrinkles
- Promote hair growth (early-stage evidence)
- Support wound healing and tissue repair
- Have anti-inflammatory and antioxidant effects
- Possible Cycle:
- 12 weeks followed by 1-2 months off, or month on month off
GHK-Cu 50 (50 mg/3ml/300units) 6 units = 1mg:
- 6–12 units nightly
AHK-CU (COPPER PEPTIDE)
- A synthetic tripeptide complexed with copper composed of:
- Alanine
- Histidine
- Lysine
- Structurally similar in concept to GHK-Cu, but with a different amino acid sequence
- Studied for its role in cell signalling and tissue regeneration pathways
- Research interest focuses on its interaction with:
- dermal and connective tissue repair mechanisms
- extracellular matrix remodelling
- angiogenesis (new blood vessel formation) signalling
- inflammatory modulation pathways
What it’s studied for
- Research commonly investigates:
- skin regeneration and repair models
- collagen and elastin production pathways
- hair follicle stimulation mechanisms
- wound healing and tissue remodeling
- anti-inflammatory signalling effects
- cosmetic and dermatological regenerative research
Cycle length (research / anecdotal use)
- Common informal / experimental research patterns
- 4–12 weeks frequently discussed
- sometimes used longer in regenerative or cosmetic research models
- Typically explored as:
- daily or near-daily administration in study designs
- or periodic dosing depending on experimental goals
AHK-Cu — 20 mg / 3 ml / 300 units
- 5 units = 0.33 mg (330 mcg)
- 10 units = 0.67 mg
- 15 units = 1 mg
- 30 units = 2 mg
Theoretical research schedule examples
- Low protocol:
- = 5 units daily (≈0.33 mg)
- Moderate protocol:
- = 10 units daily (≈0.67 mg)
- Higher research example:
- = 15 units daily (≈1 mg)
20 mg total content example longevity
- 5 units/day → ~60 days
- 10 units/day → ~30 days
- 15 units/day → ~20 days
Common research pairing
- Often discussed alongside:
- GHK-Cu
- skin regeneration peptide protocols
- hair follicle stimulation research compounds
- extracellular matrix and collagen-support models
- Due to overlapping copper-peptide signalling pathways involved in tissue repair and remodeling.
TB-500
- A synthetic peptide fragment designed to mimic Tβ4 activity
- Involved in:
- cell migration
- angiogenesis (new blood vessel formation)
- tissue repair signaling
What it’s studied for
- Research areas include:
- muscle and tendon healing
- ligament recovery
- wound healing
- inflammation reduction
- possible cardiac repair effects
Cycle length” (research / anecdotal use)
- 1. “Loading phase”
- ~2–6 weeks
- Higher frequency dosing
- 2. “Maintenance phase”
- Additional weeks or intermittent use
- Typical total duration discussed:
- 4–12 weeks
TB500 10 (10 mg/3ml/300units) 30 units = 1mg:
- 10 units nightly or 30 units 2–3x weekly
BPC-157
- A synthetic fragment derived from a protein found in human gastric juice
- Not an approved medication
- Studied mainly in animal models
- It’s often categorized as a gut-derived healing peptide
What it’s studied for
- Research suggests potential effects on:
- tendon and ligament healing
- muscle repair
- gut lining protection (ulcers, inflammation)
- nerve healing
- angiogenesis (blood vessel formation)
One unique angle
- Strong focus on gut repair + systemic healing signaling
Cycle length” (research / anecdotal use)
- Like TB-500:
Common informal/research-style use patterns:
- Duration often discussed:
- 2–6 weeks (short protocols)
- sometimes extended to 8–12 weeks
- Used either:
- continuously during that period
- or until an injury “resolves”
BPC-157 10 (10 mg/3ml/300units) 30 units = 1mg:
- 10 units nightly
KPV
- A synthetic tripeptide fragment derived from α-MSH (alpha-melanocyte stimulating hormone)
- Not an approved medication
- Studied mainly in pre-clinical / animal models and experimental settings
- It is often categorized as an anti-inflammatory / gut-associated regulatory peptide
What it’s studied for
- Research suggests potential effects on:
- gut inflammation modulation
- intestinal barrier support
- inflammatory signalling pathways
- skin inflammation models
- mucosal healing pathways
- immune regulation mechanisms
One unique angle
- Strong focus on local anti-inflammatory signalling + gastrointestinal support
Cycle length (research / anecdotal use)
- Common informal / research-style use patterns
- Duration often discussed:
- 2–4 weeks (short protocols)
- sometimes extended to 6–8 weeks
- Used either:
- continuously during that period
- or until research objective / endpoint is reached
KPV-10 (10 mg / 3 ml / 300 units). 30 units = 1 mg, take 10 units nightly for 30 days and repeat for another 30 days. Have 1 month break and cycle once again.
WOLVERINE BLEND
- A dual peptide formulation:
- BPC-157 → gut-derived, tendon/ligament + localized repair
- TB-500 → systemic repair, cell migration, angiogenesis
- The nickname comes from the Wolverine character because of his rapid healing ability.
Why they’re combined
- The idea is “synergy”:
- BPC-157:
- targets connective tissue + gut + inflammation
- TB-500:
- enhances systemic healing + cell movement + blood flow
- Together they:
- hit multiple repair pathways at once
- may improve:
- muscle recovery
- tendon/ligament healing
- inflammation control
Cycle length
- Like the individual peptides:
What’s commonly discussed (non-clinical):
- Typical duration:
- 4–8 weeks
- sometimes 6–12 weeks depending on injury severity
- Often structured as:
- continuous use during that period
- then stop or reassess
Wolverine Blend 20 (10mg BPC 157& 10mg Tb 500) (20 mg/3ml/300units) 15 units = 1mg
- 6–12 units nightly
RECOVERY BLEND
- A treble peptide formulation:
- BPC-157 → gut-derived, tendon/ligament + localized repair
- TB-500 → systemic repair, cell migration, angiogenesis
- KPV → anti-inflammatory peptide
Why they’re combined
- The idea is “synergy”:
- BPC-157:
- targets connective tissue + gut + inflammation
- TB-500:
- enhances systemic healing + cell movement + blood flow
- KPV:
- targets connective tissue + gut + inflammation
- Together they:
- hit multiple repair pathways at once
- may improve:
- muscle recovery
- tendon/ligament healing
- inflammation control
- Gut lining
Cycle length
- Like the individual peptides:
What’s commonly discussed (non-clinical):
- Typical duration:
- 4–8 weeks
- sometimes 6–12 weeks depending on injury severity
- Often structured as:
- continuous use during that period
- then stop or reassess
Recovery Blend 30 (10mg BPC 157& 10mg Tb 500 & KPV 10mg) (300 mg/3ml/300units) 10units = 1mg
- 6–12 units nightly
GLOW BLEND
- The Glow blend isn’t one official drug—it’s a combo peptide mix, almost always made of:
- GHK-Cu → skin regeneration / collagen
- BPC-157 → tissue repair + anti-inflammatory
- TB-500 → systemic healing + cell migration
- Most commonly:
- ~50 mg GHK-Cu + 10 mg BPC-157 + 10 mg TB-500
What it’s designed for (research context)
- This blend is basically trying to stack three mechanisms at once:
- Skin + cosmetic side (GHK-Cu)
- collagen, elasticity, “glow”
- Localized repair (BPC-157)
- tendons, ligaments, gut
- Systemic repair (TB-500)
- blood flow, cell migration, recovery
- In research, it’s explored for:
- tissue regeneration
- wound healing
- inflammation modulation
- skin biology / anti-aging pathways
Cycle length
- What’s commonly discussed (non-medical / anecdotal):
- 4–8 weeks most typical
- sometimes up to 12 weeks
- From community discussion:
- “cycle 4–5 weeks” (example anecdotal protocol)
- The “cycle” is completely informal, not based on human trials.
Glow 70 (10mg BPC 157, 50mg GHKCU & 10mg TB500) (70 mg/3ml/300units) 4.28 units = 1 mg
- 8–12 units nightly
KLOW BLEND”
- The Klow blend is just a variation of the Glow stack with one extra peptide added:
- GHK-Cu → skin / collagen / regeneration
- BPC-157 → localized tissue repair
- TB-500 → systemic healing
- KPV → anti-inflammatory peptide
What KPV adds
- KPV (Lys-Pro-Val) is a small peptide fragment derived from alpha-MSH
- It’s mainly studied for:
- strong anti-inflammatory effects
- immune modulation
- gut inflammation (IBD-type models)
- skin inflammation (acne, dermatitis models)
- Adding KPV turns Glow into something more inflammation-focused:
- Glow blend:
- regeneration + skin + healing
- Klow blend:
- regeneration + skin + healing + inflammation control
- The theoretical benefit:
- better for:
- irritated skin
- chronic inflammation
- gut + skin crossover issues
Cycle length
- Common anecdotal ranges:
- 4–8 weeks typical
- sometimes up to 10–12 weeks
KLOW 80 (10mg BPC 157, 50mg GHKCU, KPV 10mg & 10mg TB500) (80 mg/3ml/300units)
- 3.75 units = 1mg
- 8–12 units nightly
- Performance & Metabolic Regulation
- MOTS-c
- is a mitochondrial-derived peptide—meaning it’s encoded by mitochondrial DNA rather than nuclear DNA.
- Full name: mitochondrial open reading frame of the 12S rRNA-c
- Discovered relatively recently in metabolic research
- Plays a role in cellular energy regulation
MOTS-c is mainly researched in the context of metabolism and aging.
- Potential effects (mostly animal + early human data):
- Improved insulin sensitivity
- Enhanced glucose metabolism
- Increased fat utilization
- Support for exercise performance
- Possible anti-aging / longevity pathways
- Mechanistically, it’s linked to:
- activation of AMP-activated protein kinase (AMPK)
- regulation of metabolic stress responses
What makes it interesting
- Unlike GLP-1 drugs (semaglutide, tirzepatide):
- Doesn’t suppress appetite directly
- Works more on how your body uses energy
- Think:
- GLP-1s → “eat less”
- MOTS-c → “use energy better”
Cycle length
- 2–4 weeks short protocols
- sometimes 4–8 weeks
- Often used:
- daily or several times per week
- sometimes around training periods
MOTS-C 30 (30 mg/3ml/300units) 10 units = 1mg
- 10 units daily or 30–35 units 2x weekly (morning fasted)
SLU-PP-332
- A synthetic experimental compound studied as an ERR (Estrogen-Related Receptor) agonist
- Investigated primarily for effects on:
- metabolic signalling
- mitochondrial activity
- endurance-related pathways
- energy expenditure mechanisms
- Research interest has focused on its potential ability to influence:
- oxidative metabolism
- skeletal muscle energy utilization
- exercise-mimetic signalling pathways
- SLU-PP-332 remains:
- highly experimental
- preclinical in nature
- not an approved therapeutic agent
What it’s studied for
- Research commonly investigates:
- mitochondrial biogenesis pathways
- endurance and exercise signalling
- metabolic flexibility
- fatty acid oxidation mechanisms
- energy expenditure models
- skeletal muscle metabolic activity
Cycle length (research / anecdotal use)
- Common informal / experimental research discussions include
- 4–8 week exploratory protocols
- variable schedules depending on metabolic research objectives
- Often discussed in:
- once-daily research models
- endurance or recomposition-focused protocols
SLU-PP-332 — 10 mg / 3 ml / 300 units
- 5 units = 0.17 mg (170 mcg)
- 10 units = 0.33 mg (330 mcg)
- 15 units = 0.5 mg (500 mcg)
Theoretical research schedule examples
- Low protocol:
- = 5 units daily (≈170 mcg)
- Moderate protocol:
- = 10 units daily (≈330 mcg)
- Higher research example:
- = 15 units daily (≈500 mcg)
10 mg total content example longevity
- 5 units/day → ~60 days
- 10 units/day → ~30 days
- 15 units/day → ~20 days
Common research pairing
- Often discussed alongside:
- mitochondrial-support research compounds
- endurance-focused experimental protocols
- metabolic and recomposition research models
- Due to overlapping energy metabolism signalling interests.
SS-31 (ELAMIPRETIDE)
- A synthetic mitochondria-targeting peptide
- Studied for its interaction with cardiolipin, a phospholipid found in the inner mitochondrial membrane
- Investigated primarily for:
- mitochondrial function support
- cellular energy production pathways
- oxidative stress regulation mechanisms
- SS-31 research focuses heavily on:
- mitochondrial efficiency
- ATP production signalling
- cellular resilience and recovery models
What it’s studied for
- Research commonly investigates:
- mitochondrial bioenergetics
- oxidative stress pathways
- recovery and endurance signalling
- cellular repair mechanisms
- cardiac and skeletal muscle energy models
- neuroprotective and metabolic research applications
Cycle length (research / anecdotal use)
- Common informal / research-style discussions include
- 4–8 week protocols frequently discussed
- sometimes extended in mitochondrial-focused research models
- Often administered:
- once daily
- occasionally split into multiple administrations in experimental settings
SS-31 (Elamipretide) — 30 mg / 3 ml / 300 units
- 5 units = 0.5 mg
- 10 units = 1 mg
- 15 units = 1.5 mg
- 30 units = 3 mg
Theoretical research schedule examples
- Low protocol:
- = 5 units daily (≈0.5 mg)
- Moderate protocol:
- = 10 units daily (≈1 mg)
- Higher research example:
- = 30 units daily (≈3 mg)
30 mg total content example longevity
- 5 units/day → ~60 days
- 10 units/day → ~30 days
- 30 units/day → ~10 days
Common research pairing
- Often discussed alongside:
- mitochondrial-support compounds
- endurance-focused research protocols
- recovery and oxidative stress models
- metabolic and cellular energy pathway research
- Due to overlapping mitochondrial and bioenergetic signalling interests.
CJC-1295 (NO DAC) + IPAMORELIN
- This is a paired peptide protocol used in research contexts to stimulate natural growth hormone (GH) release.
Components:
- CJC-1295 (no DAC)
- A modified version of **growth hormone-releasing hormone
- Signals the pituitary to release GH
- Ipamorelin
- A ghrelin mimetic (growth hormone secretagogue)
- Triggers GH release without strongly increasing cortisol or prolactin
- Together:
- They synergistically increase pulsatile GH release
Why they’re combined
- Each peptide hits a different pathway:
- CJC-1295 → increases baseline GH signaling
- Ipamorelin → triggers GH pulses
- Result:
- more natural GH rhythm vs using either alone
- often described as:
- smoother
- more physiological
Cycle length
- But this combo is one of the more “structured” ones in peptide discussions.
Common informal protocols:
- 8–12 weeks typical
- sometimes extended to:
- 12–16 weeks
- Often followed by:
- a break (e.g. 4 weeks)
CJC-1295 no dac + Ipamorelin 20 (10mg Cjc-1295 & 10mg Ipamorelin) (20 mg/3ml/300units) 15 units = 1mg
- 6–12 units nightly
- Ipamorelin
- is a growth hormone secretagogue—a peptide that stimulates your body to release its own growth hormone (GH).
- It mimics the action of ghrelin
- Acts on the growth hormone secretagogue receptor (GHSR)
- Considered one of the “cleaner” GH-releasing peptides
- Key point:
- It triggers natural GH pulses rather than replacing GH directly
- Ipamorelin is studied for:
- increased growth hormone (GH) and IGF-1
- improved recovery and repair
- better sleep quality
- potential fat loss (indirect)
- mild support for lean mass
Effects are generally
- subtle
- gradual
- dependent on consistency
Cycle length
- Common informal / research-style use:
- 8–12 weeks typical
- sometimes extended to:
- 12–16 weeks
- Often followed by:
- a break period (e.g. a few weeks)
Ipamorelin 20 (20 mg/3ml/300units) 15 units = 1mg
- 6–12 units nightly
CJC-1295 (NO DAC)
- A synthetic GHRH analogue (Growth Hormone Releasing Hormone)
- Designed to stimulate the body’s natural pulsatile release of growth hormone (GH)
- Commonly researched alongside peptides like Ipamorelin
- Unlike DAC versions:
- No DAC = shorter acting
- Typically associated with:
- shorter half-life
- more pulse-like GH release patterns
- more frequent administration in research settings
What it’s studied for
- Research interest commonly includes:
- growth hormone signalling
- IGF-1 modulation
- recovery pathways
- sleep quality mechanisms
- lean tissue preservation
- exercise recovery models
- aging-related endocrine research
Cycle length (research / anecdotal use)
- Common informal / research-style patterns
- 8–12 weeks is frequently discussed
- sometimes extended longer in rotational protocols
- Often administered:
- once nightly
- or split into multiple daily pulses in some research protocols
CJC-1295 (No DAC) — 20 mg / 3 ml / 300 units
- 5 units = 0.33 mg (330 mcg)
- 10 units = 0.67 mg (670 mcg)
- 15 units = 1 mg
Theoretical research schedule examples
- Low protocol:
- = 5 units nightly (≈330 mcg)
- Moderate protocol:
- = 10 units nightly (≈670 mcg)
- Higher research example:
- = 15 units nightly (≈1 mg)
20 mg total content example longevity
- 5 units/day → ~60 days
- 10 units/day → ~30 days
- 15 units/day → ~20 days
Common research pairing
- Often discussed in combination with:
- Ipamorelin
- GHRP-class peptides
- recovery-focused protocols
- Due to complementary GH pulse signalling mechanisms.
TESAMORELIN
- A synthetic Growth Hormone Releasing Hormone (GHRH) analogue
- Designed to stimulate the body’s natural release of growth hormone (GH) and increase IGF-1 levels
- Structurally modified for improved stability and activity compared to native GHRH
- Unlike shorter acting GHRH peptides:
- Tesamorelin generally produces:
- sustained GH signalling
- increased IGF-1 response
- metabolic and body-composition research interest
What it’s studied for
- Research commonly focuses on:
- visceral fat reduction pathways
- growth hormone signalling
- IGF-1 modulation
- metabolic regulation
- recovery mechanisms
- body composition research
- cognitive and neuroprotective pathways
Cycle length (research / anecdotal use)
- Common informal / research-style patterns
- 8–12 weeks frequently discussed
- sometimes extended in longer metabolic research protocols
- Often administered:
- once daily
- commonly in evening or fasted-state research protocols
Tesamorelin — 20 mg / 3 ml / 300 units
- 5 units = 0.33 mg (330 mcg)
- 10 units = 0.67 mg (670 mcg)
- 15 units = 1 mg
Theoretical research schedule examples
- Low protocol:
- = 5 units nightly (≈330 mcg)
- Moderate protocol:
- = 10 units nightly (≈670 mcg)
- Higher research example:
- = 15 units nightly (≈1 mg)
20 mg total content example longevity
- 5 units/day → ~60 days
- 10 units/day → ~30 days
- 15 units/day → ~20 days
Common research pairing
- Often discussed alongside:
- Ipamorelin
- CJC-1295
- metabolic-focused peptide protocols
- recovery and recomposition research models
- Due to complementary GH / IGF-1 pathway interest.
IGF-1 LR3
- A synthetic analogue of Insulin-Like Growth Factor 1 (IGF-1)
- Modified with an extended amino acid chain for:
- longer half-life
- reduced binding to IGF binding proteins
- prolonged biological activity in research settings
- Unlike standard IGF-1:
- LR3 remains active significantly longer
- Often researched for anabolic and recovery-related signalling pathways
What it’s studied for
- Research commonly investigates:
- muscle cell growth signalling
- recovery and regeneration pathways
- nutrient partitioning mechanisms
- insulin sensitivity interactions
- tissue repair models
- performance and hypertrophy research
- cellular growth signalling
Cycle length (research / anecdotal use)
- Common informal / research-style patterns
- 4–6 weeks frequently discussed
- sometimes extended cautiously in longer protocols
- Often administered:
- once daily
- commonly around training-window research protocols
IGF-1 LR3 — 1 mg / 3 ml / 300 units
- 10 units = 33 mcg
Theoretical research schedule examples
- Dosing thoery
- = 10 units daily (≈33 mcg)
1 mg total content example longevity
- 10 units/day → ~30 days
Common research pairing
- Often discussed alongside:
- CJC-1295
- Ipamorelin
- growth hormone secretagogues
- recovery and hypertrophy-focused research protocols
- Due to complementary anabolic signalling pathway interest.
5-AMINO-1MQ
- (5-amino-1-methylquinolinium) is an experimental small molecule, not a peptide, that’s being studied for fat loss and metabolic regulation.
- It works by inhibiting the enzyme nicotinamide N-methyltransferase (NNMT)
- NNMT plays a role in:
- fat storage
- energy metabolism
- cellular methylation balance
- It’s designed to shift the body toward burning fat rather than storing it
Potential effects:
- reduced fat accumulation
- increased metabolic rate
- improved insulin sensitivity
- changes in energy utilization
- It’s often positioned as:
- a “metabolic enhancer”
- not an appetite suppressant (unlike GLP-1 drugs)
- How it’s different from GLP-1 drugs
| Compound | Main mechanism |
|---|---|
| Semaglutide | Appetite suppression |
| Tirzepatide | Appetite + insulin |
| MOTS-c | Cellular energy regulation |
| 5-Amino-1MQ | Fat metabolism via NNMT inhibition |
- GLP-1 → eat less
- 5-Amino-1MQ → burn differently
Cycle length
- 4–8 weeks typical
- sometimes extended to 8–12 weeks
5-Amino-1MQ 50 (50 mg/3ml/300units) 6 units = 1mg
- 10-20 units- morning fasted
- Immunity & Longevity
- Epithalon
- Is (also called Epitalon or Epithalone) is a synthetic peptide derived from a natural peptide called Epithalamin, which comes from the pineal gland.
- Short peptide: 4 amino acids
- Developed in Russia for aging and longevity research
- Often grouped with “anti-aging peptides”
- Potential effects studied:
- activation of telomerase
- possible telomere length support
- improved sleep regulation (via melatonin pathways)
- antioxidant effects
- potential lifespan extension (in animals)
- Big claim:
- It may influence biological aging processes
How it works (simplified)
- Epithalon is thought to:
- act on the pineal gland
- influence melatonin production
- regulate genes linked to aging and cell cycles
Cycle length
- 10–20 days per cycle some extend to 30 days.
- repeated:
- 1–2 times per yea
Why people use it
- anti-aging / longevity
- improved sleep quality
- circadian rhythm support
- general “recovery” feeling
Epithalon 50 (50 mg/3ml/300units) 6 units= 1mg
- 10-20 units nightly
Thymosin Alpha-1 is a naturally occurring peptide derived from the thymus gland.
- It’s a fragment of prothymosin alpha
- Plays a role in immune system regulation
- Unlike many peptides you’ve asked about, this one actually has clinical use in some countries
What it’s used for (medical + research)
- TA-1 has been studied and used for:
- immune system support
- chronic viral infections (e.g. hepatitis B/C)
- adjunct therapy in cancer treatment
- immune recovery in weakened states
- It works by:
- enhancing T-cell function
- improving immune signalling and response
How it works (simplified)
- Thymosin Alpha-1 helps:
- activate immune cells (especially T lymphocytes)
- regulate cytokines (immune signalling molecules)
- improve the body’s ability to respond to infections
Cycle length
- This one is different because it does have real clinical protocols.
In medical use:
- Often used for:
- several weeks to months
- Example patterns:
- 6–12 weeks common
- sometimes longer depending on condition
Thymosin Alpha-1 20 (20 mg/3ml/300units) 15 units = 1mg
- 30 units 3 x week
PNC-27
- A synthetic experimental peptide studied in oncology-related research
- Designed to interact with HDM-2 (human double minute 2) associated pathways
- Investigated for selective interactions with certain cancer-cell membrane targets in preclinical models
- PNC-27 research remains:
- highly experimental
- primarily preclinical
- not an approved therapeutic agent
What it’s studied for
- Research commonly investigates:
- cancer-cell targeting mechanisms
- membrane pore formation models
- apoptosis and necrosis signalling pathways
- HDM-2 interaction mechanisms
- selective tumor-cell response models
- experimental oncology applications
Cycle length (research / anecdotal use)
- Common informal / experimental research-style discussions include
- 2–6 week exploratory protocols
- variable schedules depending on research design
- Administration frequency in discussions varies widely due to the experimental nature of the compound.
PNC-27 — 10 mg / 3 ml / 300 units
- 5 units = 0.17 mg (170 mcg)
- 10 units = 0.33 mg (330 mcg)
- 15 units = 0.5 mg (500 mcg)
Theoretical research schedule examples
- Low protocol:
- = 5 units daily (≈170 mcg)
- Moderate protocol:
- = 10 units daily (≈330 mcg)
- Higher research example:
- = 15 units daily (≈500 mcg)
10 mg total content example longevity
- 5 units/day → ~60 days
- 10 units/day → ~30 days
- 15 units/day → ~20 days
Common research discussion areas
- Often referenced alongside:
- experimental oncology peptides
- targeted signalling pathway research
- cellular apoptosis and membrane-interaction studies
- Due to its investigational cancer-cell targeting mechanisms.
DSIP (DELTA SLEEP-INDUCING PEPTIDE)
- A naturally occurring neuropeptide originally isolated in sleep-related research
- Studied for potential involvement in:
- sleep regulation
- stress response pathways
- neuroendocrine signalling
- DSIP research is primarily associated with:
- sleep architecture studies
- relaxation and recovery signalling
- circadian and CNS regulatory mechanisms
What it’s studied for
- Research commonly investigates:
- sleep quality pathways
- recovery and relaxation signalling
- stress modulation mechanisms
- circadian rhythm regulation
- neuroendocrine interactions
- fatigue and recovery models
Cycle length (research / anecdotal use)
- Common informal / research-style patterns
- 2–6 weeks frequently discussed
- sometimes used intermittently based on sleep-focused protocols
- Often administered:
- nightly
- typically prior to sleep-focused research periods
DSIP — 10 mg / 3 ml / 300 units
- 5 units = 0.17 mg (170 mcg)
- 10 units = 0.33 mg (330 mcg)
- 15 units = 0.5 mg (500 mcg)
Theoretical research schedule examples
- Low protocol:
- = 5 units nightly (≈170 mcg)
- Moderate protocol:
- = 10 units nightly (≈330 mcg)
- Higher research example:
- = 15 units nightly (≈500 mcg)
10 mg total content example longevity
- 5 units/day → ~60 days
- 10 units/day → ~30 days
- 15 units/day → ~20 days
Common research pairing
- Often discussed alongside:
- CJC-1295
- Ipamorelin
- recovery-focused peptide protocols
- sleep and CNS-support research models
- Due to overlapping recovery and restorative signalling interests.
Hormonal Compounds
Testosterone cypionate is a long-acting ester of testosterone used in testosterone replacement therapy (TRT).
- It’s a form of testosterone
- Designed for slow release after injection
- Commonly prescribed for clinically low testosterone (hypogonadism)
What TRT with testosterone cypionate does
- TRT aims to restore testosterone to a normal physiological range.
- Potential benefits:
- improved energy
- increased libido
- better mood
- improved muscle mass and strength
- increased bone density
Cycle length
- TRT is NOT a cycle
- This is the biggest difference from everything else you’ve asked about.
- ❌ Not 8–12 weeks
- ❌ Not on/off
- ✅ Long-term (often lifelong) therapy
- TRT = continuous hormone replacement, not cycling
- Stopping TRT:
- testosterone levels drop back to baseline (often low again)
- symptoms return
📊 Typical TRT dosing (medical context)
- Usually:
- 100–200 mg per week
- Injection frequency: micro dosed daily or every other day
- TRT typically shuts down natural testosterone production
Fertility note
- TRT can significantly reduce sperm production
- Sometimes managed with:
- human chorionic gonadotropin (hCG)
- TRT vs “cycling steroids”
| TRT | Steroid cycle |
|---|---|
| Medical | Performance use |
| Stable hormone levels | Supraphysiological levels |
| Long-term | Short-term |
| Health-focused | Performance-focused |
- TRT = replacement, not enhancement
TRT Testosterone Cypionate 750(750 mg/3ml/300units) 0.4 units = 1mg
- 6-9 units daily or 12-18 units alternate days
KISSPEPTIN-10
- A synthetic fragment of the naturally occurring kisspeptin peptide family
- Studied for its role in regulating the hypothalamic–pituitary–gonadal (HPG) axis
- Associated with signalling involved in reproductive hormone release
- Kisspeptin research primarily focuses on:
- stimulation of GnRH (Gonadotropin-Releasing Hormone) pathways
- downstream effects on:
- LH (Luteinizing Hormone)
- FSH (Follicle-Stimulating Hormone)
- testosterone and reproductive hormone signalling
What it’s studied for
- Research commonly investigates:
- reproductive endocrine signalling
- testosterone regulation pathways
- fertility and gonadal function models
- HPG-axis modulation
- pituitary hormone signalling
- hypothalamic regulation mechanisms
Cycle length (research / anecdotal use)
- Common informal / research-style patterns
- 2–6 weeks frequently discussed
- often used in shorter endocrine-focused protocols
- Often administered:
- once daily
- or in intermittent pulse-style research schedules
Kisspeptin-10 — 10 mg / 3 ml / 300 units
- 5 units = 0.17 mg (170 mcg)
- 10 units = 0.33 mg (330 mcg)
- 15 units = 0.5 mg (500 mcg)
Theoretical research schedule examples
- Low protocol:
- = 5 units daily (≈170 mcg)
- Moderate protocol:
- = 10 units daily (≈330 mcg)
- Higher research example:
- = 15 units daily (≈500 mcg)
10 mg total content example longevity
- 5 units/day → ~60 days
- 10 units/day → ~30 days
- 15 units/day → ~20 days
Common research pairing
- Often discussed alongside:
- HCG
- enclomiphene
- gonadorelin
- fertility and endocrine-focused peptide protocols
- Due to overlapping reproductive hormone signalling pathways.
PT-141 (BREMELANOTIDE)
- A synthetic melanocortin peptide analogue
- Derived from modifications of Melanotan II research peptides
- Studied primarily for effects related to:
- sexual function signalling
- arousal pathways
- central nervous system melanocortin receptor activity
- Unlike PDE5-focused compounds:
- PT-141 research focuses more on:
- central neurological signalling
- melanocortin receptor activation
- libido and arousal mechanisms
What it’s studied for
- Research commonly investigates:
- sexual arousal pathways
- libido signalling
- melanocortin receptor activity
- CNS-mediated sexual function mechanisms
- erectile function models
- female sexual function research
Cycle length (research / anecdotal use)
- Common informal / research-style patterns
- often used as-needed in research settings
- sometimes studied intermittently over 4–8 week periods
- Typically not discussed as a continuous daily protocol.
PT-141 — 20 mg / 3 ml / 300 units
- 5 units = 0.33 mg (330 mcg)
- 10 units = 0.67 mg (670 mcg)
- 15 units = 1 mg
- 30 units = 2 mg
Theoretical research schedule examples
- Low protocol:
- = 10 units as needed (≈670 mcg)
- Moderate protocol:
- = 15 units as needed (≈1 mg)
- Higher research example:
- = 30 units as needed (≈2 mg)
20 mg total content example longevity
- 10 units/use → ~30 uses
- 15 units/use → ~20 uses
- 30 units/use → ~10 uses
Common research pairing
- Often discussed alongside:
- Melanotan peptides
- libido-focused research compounds
- erectile function pathway research protocols
- Due to overlapping melanocortin signalling mechanisms.
DSIP (DELTA SLEEP-INDUCING PEPTIDE)
- A naturally occurring neuropeptide originally isolated in sleep-related research
- Studied for potential involvement in:
- sleep regulation
- stress response pathways
- neuroendocrine signalling
- DSIP research is primarily associated with:
- sleep architecture studies
- relaxation and recovery signalling
- circadian and CNS regulatory mechanisms
What it’s studied for
- Research commonly investigates:
- sleep quality pathways
- recovery and relaxation signalling
- stress modulation mechanisms
- circadian rhythm regulation
- neuroendocrine interactions
- fatigue and recovery models
Cycle length (research / anecdotal use)
- Common informal / research-style patterns
- 2–6 weeks frequently discussed
- sometimes used intermittently based on sleep-focused protocols
- Often administered:
- nightly
- typically prior to sleep-focused research periods
DSIP — 10 mg / 3 ml / 300 units
- 5 units = 0.17 mg (170 mcg)
- 10 units = 0.33 mg (330 mcg)
- 15 units = 0.5 mg (500 mcg)
Theoretical research schedule examples
- Low protocol:
- = 5 units nightly (≈170 mcg)
- Moderate protocol:
- = 10 units nightly (≈330 mcg)
- Higher research example:
- = 15 units nightly (≈500 mcg)
10 mg total content example longevity
- 5 units/day → ~60 days
- 10 units/day → ~30 days
- 15 units/day → ~20 days
Common research pairing
- Often discussed alongside:
- CJC-1295
- Ipamorelin
- recovery-focused peptide protocols
- sleep and CNS-support research models
- Due to overlapping recovery and restorative signalling interests.
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- NAD⁺
- Is (nicotinamide adenine dinucleotide) is a coenzyme found in every cell of your body and is essential for energy production and cellular health.
- Central to cellular respiration
- Required for:
- converting food into energy (ATP)
- DNA repair
- cell signaling
- NAD⁺ = fuel system regulator for your cells
What it’s studied for
- NAD⁺ has become popular in aging and metabolic research.
- Potential roles:
- improved mitochondrial function
- enhanced energy levels
- support for brain function
- DNA repair and longevity pathways
- possible benefits in addiction recovery (studied clinically in some settings)
- It interacts with:
- sirtuins (linked to aging and metabolism)
Why NAD⁺ declines
- Levels naturally decrease with:
- aging
- stress
- poor metabolic health
- Lower NAD⁺ is associated with:
- fatigue
- reduced metabolic efficiency
- impaired cellular repair
Cycle length
- NAD⁺ isn’t really a “cycle compound” in the traditional sense
Different forms:
- 1. IV / injectable NAD⁺
- Often used in:
- short protocols
- multiple infusions
2. Oral precursors (more common)
- nicotinamide riboside
- nicotinamide mononucleotide
- These are typically:
- taken daily, long-term
- not cycled
Expected effects
- mild increase in energy
- improved recovery feeling
- subtle cognitive benefits
- Important:
effects are usually subtle, not dramatic
- NAD⁺ itself is biologically natural
- Precursors (NR, NMN) are generally well tolerated
- But:
- long-term high-dose effects still being studied
- IV NAD⁺ clinics vary widely in quality
NAD 1000 (1000 mg/3ml/300units) 0.3 units = 1mg
- 10–15 units daily or 15–30 units alternate days
HGH
- Is (Human Growth Hormone) is a naturally occurring hormone produced by the pituitary gland.
- Scientific name: growth hormone
- It regulates:
- growth
- metabolism
- tissue repair
- body composition
- Medical version:
- Somatropin (bioidentical HGH)
What HGH does in the body
- HGH works both directly and through another hormone:
- stimulates liver to produce insulin-like growth factor 1 (IGF-1)
- IGF-1 drives many of the anabolic and recovery effects
Effects:
- increased protein synthesis
- fat metabolism (lipolysis)
- tissue repair and regeneration
- improved bone density
- HGH is prescribed for:
- growth hormone deficiency
- certain genetic conditions
- muscle wasting diseases
- In these cases:
- it’s used as long-term therapy, similar to TRT
Cycle length
- Medically:
- ❌ not cycled
- ✅ continuous, long-term use
Performance / non-medical use:
- People often talk about “cycles,” but:
common informal durations
- 3–6 months minimum
- often 6–12+ months
- Why longer?
- HGH works slowly
- effects take months, not weeks
HGH 100iu (100iu/3ml/300units) 3 units = 1iu
- 9–18 units daily
HCG
- Is (human chorionic gonadotropin) is a hormone that mimics luteinizing hormone (LH) in the body.
- Naturally produced during pregnancy
- In men, it stimulates the testes to produce:
- testosterone
- sperm
- Think of it as:
- a signal to “turn the testes back on”
What hCG is used for
- Medical uses:
- male hypogonadism
- fertility treatment
- delayed puberty
Common non-medical contexts:
- alongside TRT
- post-cycle therapy (PCT)
Why it’s used with TRT
- When someone uses TRT (like testosterone cypionate):
- natural LH production shuts down
- testes stop producing testosterone
- can lead to:
- testicular shrinkage
- reduced fertility
- hCG helps:
- maintain testicular function
- preserve fertility (partially)
- keep some natural testosterone production active
Cycle length (depends on use)
- 1. With TRT (ongoing use)
- Not really cycled
- used continuously alongside TRT
- long-term protocol
2. Post-cycle therapy (PCT)
- Short-term use
- typically 2–4 weeks
- used to restart natural production before
HCG 10000IU (10000iu/3ml/300units) 3 units = 100iu
- 15 units 3 x per week
Cognitive Peptides
- Semax
- is a synthetic peptide nootropic derived from a fragment of adrenocorticotropic hormone (ACTH 4–10).
- Developed in Russia
- Used there clinically (e.g. stroke recovery, cognitive disorders)
- Typically administered as a nasal spray/Sub q Inj
- It’s not a stimulant like caffeine—more of a neuroregulatory peptide
What Semax does
- Semax affects several brain pathways:
- increases brain-derived neurotrophic factor (BDNF)
- modulates dopamine and serotonin
- supports neuroprotection
- In simple terms:
- It helps with focus, memory, and brain resilience
What it’s used for
- Clinical / research use:
- stroke recovery
- cognitive impairment
- neuroprotection
Nootropic use (informal):
- improved focus
- mental clarity
- learning and memory
- reduced brain fog
Cycle length
- No official global standard, but Semax is more structured than most peptides.
Common use patterns:
- 2–4 weeks typical
- sometimes extended to:
- 4–6 weeks
- followed by:
- a break period (e.g. 1–2+ weeks)
- Short cycles with breaks are commonly used
Dosing style
- Usually Sub Q Inj
- Taken:
- Once daily
- Fast-acting:
effects can be noticed within hours to days
- Effects (realistic)
- increased focus and mental energy
- improved memory recall
- smoother cognition (not jittery)
- subtle mood lift
- Compared to stimulants:
- less “wired”
- more stable and clean feeling
Semax 20 (20 mg/3ml/300units) 15 units = 1mg
- 15 units daily
SELANK
- is a synthetic peptide developed in Russia, derived from a fragment of an immune peptide called tuftsin.
- Designed primarily as an anxiolytic (anti-anxiety) peptide
- Typically used as a nasal spray
- Often grouped with nootropic peptides like Semax
- Think of it as:
- a calming, stabilizing brain peptide (not a sedative)
What Selank does
- Selank influences several brain systems:
- modulates gamma-aminobutyric acid (GABA)
- affects serotonin and dopamine balance
- may increase BDNF (neuroplasticity support)
- In simple terms:
- reduces anxiety
- improves emotional stability
- supports cognition indirectly
What it’s used for
- Clinical / research use:
- anxiety disorders
- stress-related conditions
- cognitive support
Nootropic use (informal):
- anxiety reduction without sedation
- improved focus (by lowering mental noise)
- mood stabilization
- social anxiety support
Cycle length
- No universal standard, but commonly structured:
Typical use:
- 2–4 weeks
- sometimes extended to:
- 4–6 weeks
- followed by:
- a break period
- So:
- Short cycles with breaks are standard practice
Dosing style
- Sub Q Inj
- Taken:
- Once daily
Effects
- can be felt within:
- hours to days
- builds gradually with consistent use
Effects (realistic)
- reduced anxiety (without drowsiness)
- calmer mental state
- improved focus (indirectly)
- better stress tolerance
- Compared to medications:
- not as strong as prescription anxiolytics
- but fewer side effects and no sedation
- Selank vs Semax (key difference)
| Peptide | Effect |
|---|---|
| Semax | Stimulating / focus |
| Selank | Calming / anti-anxiety |
- Combined use:
- balances focus + calm
- common in “Know blends”
Selank 20 (20 mg/3ml/300units) 15 units = 1m
- 15 units daily
Melanocortin Peptides
Melanotan II (MT-2)
- is a synthetic peptide analogue of alpha-MSH.
- Designed to stimulate melanin production
- Also affects other receptors in the body (not just skin)
- This is why it has more side effects than Melanotan I
- In simple terms:
- It’s a potent tanning peptide with systemic effects
What it does
- Primary effect:
- increases skin pigmentation (tanning)
Secondary effects (due to broader receptor activity):
- increased libido
- spontaneous erections (in men)
- appetite suppression (mild)
Cycle length
- Common informal structure:
- 1. Loading phase
- ~7–14 days
- frequent dosing
- goal: build baseline pigmentation
- 2. Maintenance phase
- lower frequency dosing
- used to maintain tan
Total duration:
- usually 4–8 weeks
- sometimes longer depending on goals
How fast it works
- initial effects:
- within a few days (flushing, nausea)
- visible tanning:
- 1–3 weeks
- requires:
- some UV exposure for full effect
- It enhances tanning, not replaces sunlight completely
Expected results
- deeper, faster tan
MT-2 20 (20 mg/3ml/300units) 15 units = 1mg
- Days 1–10 = 5 units daily
- 10 units 2-3 times per week
GLUTATHIONE
- A naturally occurring antioxidant composed of:
- glutamine
- cysteine
- glycine
- Found in nearly all cells and heavily involved in:
- oxidative stress regulation
- detoxification pathways
- cellular redox balance
- Research interest commonly focuses on:
- antioxidant defence systems
- liver and cellular detoxification mechanisms
- mitochondrial protection pathways
- recovery and immune-support signalling
What it’s studied for
- Research commonly investigates:
- oxidative stress reduction
- cellular detoxification pathways
- mitochondrial support mechanisms
- immune system signalling
- recovery and fatigue models
- skin and pigmentation pathways
- liver-support research applications
Cycle length (research / anecdotal use)
- Common informal / research-style patterns
- 4–12 week protocols frequently discussed
- sometimes used intermittently or continuously in antioxidant-focused research models
- Often administered:
- daily
- or several times weekly depending on research objective
Glutathione — 1200 mg / 3 ml / 300 units 25 units = 100 mg
Theoretical research schedule examples
- Moderate protocol:
- = 25 units daily (≈100 mg)
- Higher research example:
- = 50 units daily (≈200 mg)
1200 mg total content example longevity
- 25 units/day → ~12 days
- 50 units/day → ~6 days
Common research pairing
- Often discussed alongside:
- NAD+ research compounds
- mitochondrial-support peptides
- recovery and detoxification-focused protocols
- antioxidant and cellular resilience research models
- Due to complementary oxidative stress and cellular protection pathways.
VITAMIN B12 (CYANOCOBALAMIN / METHYLCOBALAMIN)
- A water-soluble essential vitamin involved in:
- red blood cell formation
- neurological function
- DNA synthesis
- energy metabolism
- In research and clinical contexts, B12 is commonly studied for:
- fatigue and energy metabolism
- cognitive and neurological support pathways
- hematologic (blood-related) function
- methylation cycle support
What it’s studied for
- Research commonly investigates:
- energy metabolism and ATP production support
- nerve function and myelin maintenance
- homocysteine metabolism (methylation pathways)
- anemia-related physiology
- cognitive performance and fatigue models
Cycle length (research / general use patterns)
- Common informal / clinical-style patterns
- 4–12 weeks for deficiency correction models
- or ongoing maintenance protocols in supplementation contexts
- Often administered:
- daily
- or several times weekly depending on study design or deficiency severity
Vitamin B12 — 3000 mcg / 3 ml / 300 units 25 units = 250 mcg 50 units = 500 mcg
Theoretical research schedule examples
- Moderate protocol:
- = 25 units daily (≈250 mcg)
- Higher research example:
- = 50 units daily (≈500 mcg)
3000 mcg total content example longevity
- 25 units/day → ~12 days
- 50 units/day → ~6 days
Common research pairing
- Often discussed alongside:
- B-complex vitamins
- NAD+ support protocols
- metabolic and energy-focused supplementation models
- recovery and fatigue-reduction research contexts
- Due to overlapping roles in cellular energy and methylation pathways.